Catedral de Cádiz hasta 1838 y actualmente llamada  Iglesia de Santa Cruz. Es obra de Cristóbal de Rojas y fue finalizada en 1602. Es de planta rectangular, con falso crucero y tres naves separadas por columnas de orden toscano. De su interior destaca el retablo del altar mayor, la Capilla de los Genoveses y la Urna y Cristo del Santo Entierro. Junto a esta iglesia encontramos el Museo Catedralicio.

It was the cathedral of Cadiz until 1838. Built by Cristóbal de Rojas who finished it in 1602, nowadays it is known as the Santa Cruz Church. The ground plan has a rectangular shape and its elevation shows pseudo-crossings and three naves separated by Tuscan columns. The altarpiece, the Genovese Chapel, the Urn and the Christ of the Holy Burial are remarkable figures in the inner. Next to the church there is the Cathedral's Museum.